Treatment and remedies of COVID-19
disease
- Convalescent Plasma
- Dexamethasone Effective
- Ibuprofen
- Chloroquine/ Hydroxychloroquine And Azithromycin
- Remdesivir Effective
- Vitamin D
- Serologic (Antibody) Testing
- High-Dose Vitamin C
Convalescent Plasma
Convalescent plasma - literally
plasma from recovered patients - has been used for more than 100 years to treat
a variety of diseases from measles to polio, chickenpox, and SARS. In the
current situation, the plasma containing the antibody is given by a patient who
was cured by blood transfusion to a patient with COVID-19. Donor antibodies
help the patient fight the disease, possibly shortening the duration or
reducing the severity of the disease.
Although convalescing plasma has
been used for many years, and with varying successes, little is known about its
effectiveness in treating COVID-19. There have been reports of success from
China, but no randomized controlled studies (Gold Standard for Research
Studies) were conducted. Experts also do not know the best time during illness
to give plasma.
Dexamethasone Effective
A recent report on a clinical
trial showed that dexamethasone corticosteroid reduces the risk of death in
COVID-19 patients with severe disease. The report was published before the
study was published in a medical journal, which means that the search results
were not subject to the usual rigorous review.
Many doctors, including doctors
in the United States, treat COVID-19 patients with corticosteroids since the
epidemic began. It is biologically logical for patients who have developed a
severe immune response (cytokine storm) to viral infection. In these cases, it
is the excessive reaction of the immune system that damages the lungs and other
organs, and often leads to death.
Dexamethasone and other
corticosteroids (prednisone and methylprednisolone) are powerful
anti-inflammatory drugs. It is readily available and inexpensive.
Ibuprofen
The World Health Organization
initially recommended that acetaminophen be used in place of ibuprofen to help
reduce fever, aches, and pain associated with coronavirus infection, but it now
states that acetaminophen or ibuprofen can be used. Rapid changes in
recommendations create uncertainty. Since some doctors are still concerned
about NSAIDs, it is still wise to choose acetaminophen first, with a total dose
not to exceed 3000 milligrams per day.
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Chloroquine/ Hydroxychloroquine And Azithromycin
Hydroxychloroquine and
chloroquine are used primarily to treat malaria and many inflammatory diseases,
including lupus and rheumatoid arthritis. Azithromycin is an antibiotic
commonly prescribed for bacterial sore throat and bacterial pneumonia. Both
drugs are inexpensive and readily available.
Hydroxychloroquine and
chloroquine have been shown to kill COVID-19 in a laboratory dish. The drugs
seem to work through two mechanisms. First, they make it difficult for the
virus to stick to the cell, preventing the virus from entering the cell and
multiplying inside it. Second, if the virus can enter the cell, medications
kill them before they multiply.
Azithromycin is never used for
viral infection. However, this antibiotic does have some anti-inflammatory
action. There has been speculation, although never proven, that azithromycin
may help inhibit the excessive immune response to COVID-19 infection.
Remdesivir Effective
Remdesivir inhibitor is the
ability of coronavirus that infects SARS and MERS cells in a laboratory dish.
The drug was also effective in treating these coronavirus in animals: there was
a decrease in the amount of the virus in the body, as well as an improvement in
the lung disease caused by the virus. The drug appears to be effective in the
laboratory, in protecting cells from infection with COVID (as is the case with
SARS and coronaviruses), but more studies are ongoing to confirm this.
Vitamin D
Vitamin D may protect COVID-19 in
two ways. First, it may help enhance our body's natural defense against viruses
and bacteria. Second, it may help prevent an exaggerated inflammatory response,
which has been shown to contribute to severe disease in some people with
COVID-19.
Our bodies make vitamin D when
exposed to sunlight. Five to 10 minutes of sun exposure on some or most days of
the week for arms, legs, or back without sunscreen will enable you to produce
enough vitamin. Good nutritional sources of vitamin D include fatty fish (such
as tuna, mackerel, and salmon), foods fortified with vitamin D (such as dairy
products, soy milk, and grains), cheese, and egg yolks.
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The idea that a high dose of
vitamin C IV may help in overwhelming infections is not new. A study conducted
in 2017 found that high-dose vitamin C IV therapy (along with thiamine and
corticosteroids) seemed to prevent deaths among people with septicemia, a form
of overwhelming infection that causes low blood pressure and a serious organ
failure. Another study published last year evaluated the effect of high doses
of vitamin C injections between patients with severe infections and those with
sepsis and acute respiratory distress syndrome (ARDS), where the lungs are
filled with fluid. While the main measures of improvement for the study did not
improve during the first four days of treatment with vitamin C.
There was a lower death rate of
28 days among treated patients. Although none of these studies have considered
the use of vitamin C in patients with COVID-19, vitamin therapy has been
specifically given to sepsis and ARDS, and these are the most common conditions
that lead to intensive care unit entry, ventilator support, or Death among
those with severe COVID-19 infection.
Serologic (Antibody) Testing
A serological test is a blood
test that looks for the antibodies created by the immune system. There are many
reasons to make antibodies, the most important of which is to help fight
infection. The serological test for COVID-19 specifically looks for antibodies
against COVID-19 virus.
Serological tests may also
provide information about whether people become immune to coronavirus once they
recover, and if so, how long does this immunity last. Over time, these tests
can be used to determine who can safely return to society. Scientists can also
study coronavirus antibodies to identify the parts of the coronavirus that the
immune system responds to, giving them clues as to which part of the virus they
target in the vaccines they develop.
Serological tests are emerging
and are being developed by many private companies around the world. However,
the accuracy of these tests must be verified before they are widely used in the
United States.
Herbal treatment at home
of COVID-19
In analyzing the frequency of
herbs,
- Glycyrrhizae
- Radix et Rhizoma,
- Armeniacae Semen Amarum,
- Ephedrae Herba
- and Gypsum Fibrosum
were found as herbs with a high frequency for use in
Chinese guidelines.
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